Influencia de la fecundación in vitro en los resultados maternos y neonatales en mujeres con edad materna avanzada

Autores

Palavras-chave:

Embarazo, Edad Materna, Morbilidad, Resultado del Embarazo, Técnicas Reproductivas, Fertilización in Vitro

Resumo

Establecer el efecto de la fecundación in vitro en la frecuencia de complicaciones maternoneonatales en gestantes con edad mayor o igual de 40 años. Métodos: Casos y controles anidados en cohorte, con recogida de datos retrospectiva y seguimiento prospectivo. Cohorte total de 207 gestantes. Casos o subcohorte con fecundación in vitro y grupo control con gestación espontánea. Se realizaron pruebas paramétricas y no paramétricas para determinar la asociación potencial entre las variables.
Resultados: Las mujeres que lograron su gestación mediante fecundación in vitro tuvieron una edad media mayor (p = 0,03). En los casos fue más frecuente la primiparidad (44,4 % vs. 22,2 %, p = 0,02), la tasa de diabetes gestacional RR = 2,83 (IC
95 %: 1,19-6,77; p = 0,023) y la tasa de cesáreas (p = 0,05). En las gestaciones espontáneas se observó mayor frecuencia de inicio de trabajo de parto espontáneo (56,86 % vs. 37,03 %, p = 0,019). No se encontraron diferencias en la prevalencia de diabetes pregestacional, estados hipertensivos del embarazo, prematuridad, restricción de crecimiento intrauterino, macrosomía fetal, test de Apgar, pH patológico, ingresos neonatales y hemorragia posparto. La tasa de mortalidad perinatal fue mayor en el grupo con gestación lograda mediante fecundación in vitro. Conclusión: La concepción por fecundación in vitro en una población gestante con edad materna avanzada confiere un riesgo añadido a la misma en los resultados adversos maternos y neonatales.

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Publicado

2022-09-01

Como Citar

María Ortiz, J. S., Álvarez Silvares, E., & Bermúdez González, M. (2022). Influencia de la fecundación in vitro en los resultados maternos y neonatales en mujeres con edad materna avanzada. Revista De Obstetricia Y Ginecología De Venezuela, 82(3), 329–339. Obtido de http://caelum.ucv.ve/ojs/index.php/rev_ogv/article/view/24388