Rue and clove microspheres: antiamebic activity, hemocompatibility, and release kinetics

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Publicado: Jul 11, 2022
Palabras clave:
Alginate, drug release, herbal compounds, microspheres, parasitic activities

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Euridice Ladisu Mejía-Argueta
Autonomous University of the State of Mexico (UAEMex). Toluca, Mexico. Toxicology Laboratory, Pharmacy Department, Faculty of Chemistry, UAEMex
https://orcid.org/0000-0003-0137-498X
Jonnathan Guadalupe Santillán-Benítez
Miriam Flores-Merino
https://orcid.org/0000-0003-0793-0940
Claudia Cervantes-Rebolledo
UICUI. Ixtlahuaca, State of Mexico. Zipcode: 50740
https://orcid.org/0000-0001-5914-3047
Mario Nequiz-Avendaño
National Autonomous University of Mexico (UNAM). Experimental Medicine Research Unit, Faculty of Medicine and General Hospital “Dr. Eduardo Liceaga”. Zipcode: 067720
https://orcid.org/0000-0003-2818-2267

Resumen

Objectives:The alginate microspheres were prepared with methanol extract of rue and essential oil of clove with metronidazole evaluating their biological and physicochemical activities. Materials and methods: Microspheres were evaluated with their sphericity, encapsulation efficiency, degradation, and release kinetics with mathematical models.

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Mejía-Argueta, E. L. ., Santillán-Benítez, J. G. ., Flores-Merino, M. ., Cervantes-Rebolledo, C. ., & Nequiz-Avendaño, M. . (2022). Rue and clove microspheres: antiamebic activity, hemocompatibility, and release kinetics. Gaceta Médica De Caracas, 130(2). Recuperado a partir de http://caelum.ucv.ve/ojs/index.php/rev_gmc/article/view/24054
Número
Vol. 130 Núm. 2 (2022)
Sección
ARTÍCULOS ORIGINALES
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Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial 4.0.