Cut-off Point of Ki-67 Proliferation Marker in Differentiating Premalignant and Malignant Prostatic Lesions

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Publicado: Jun 2, 2022
Palabras clave:
Cut-Off point, Ki-67 immunohistochemistry, malignant, premalignant, prostate lesions

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Lidya Imelda Laksmi
Department of Anatomical Pathology, Faculty of Medicine, Universitas Sumatera Utara, Indonesia
http://orcid.org/0000-0002-2390-1499
Syafrudin Ilyas
Department of Biology, Universitas Sumatera Utara, Indonesia
Nurjati Chairany Siregar
Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Indonesia
Arlinda Sari Wahyunio
Department of Public Health, Universitas Sumatera Utara, Indonesia
http://orcid.org/0000-0002-5265-4685

Resumen

Immunohistochemistry Ki-67 is a marker of cell proliferation. Using immunohistochemical markers can be helpful to determine and diagnose prostate intraepithelial neoplasia (PIN) and carcinoma prostate. There are many studies about Ki67 as a prognostic tool, a diagnostic tool, and a potential therapeutic target for cancer therapy, but there are no standard criteria to define the cut-off point for the value of Ki-67 in premalignant and malignant prostate lesions.

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Cómo citar
Laksmi, L. I., Ilyas, S., Siregar, N. C., & Wahyunio, A. S. (2022). Cut-off Point of Ki-67 Proliferation Marker in Differentiating Premalignant and Malignant Prostatic Lesions. Gaceta Médica De Caracas, 130(1 S), S60-S63. Recuperado a partir de http://caelum.ucv.ve/ojs/index.php/rev_gmc/article/view/23884
Número
Vol. 130 Núm. 1 S (2022)
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