Assessing the possible impact of patient’s demographic data on coronavirus symptoms

Authors

Keywords:

Coronavirus, demographic data, age, gender, symptoms.

Abstract

Background and objective: A novel COVID-19 condition emerged in December 2019 and has held a dangerous prognosis. It started as an epidemic in China, particularly in Wuhan city. The ages of individuals prone to infection range from one-month-old to above 90 years. However, fewer cases were reported in kids and newborns. Peoples susceptible to infection are the aged, those taking immunosuppressive agents. Usually, Coronavirus holds flu symptoms, including fever (80-90%), dry cough (50%), and lethargy (20-40%); other symptoms include diarrhea. This survey intended to assess the impact of patients’ gender, age, and living circumstances on Coronavirus infection symptoms and evaluate a relationship amongst symptoms of patients with Coronavirus infection. Method: In the present survey, the authors have adopted a quantitative survey method, relying upon face-to-face personal interviews, to receive information from the internal hospital consultant in Iraq. The span of data collection was three weeks. One hundred patients were randomly engaged in this research. The study was carried on special closed topics regarding the patients’ demographic data (age and gender) and some common signs of COVID-19 “sore throat, fever, shortness of breath, headache, dry cough, wet cough, arthralgia, as well as diarrhea”. Results: A sum of 100 cases participated in this research. The reliability value was (0.733). The Chi-Square test revealed no statistically substantial connection between symptoms of Coronavirus among cases and the patients' demographics data (gender and age). Furthermore, the Chi-Square test explained that there was no statistically vital connection amongst symptoms of cases of Coronavirus (shortness of breath & Dry cough, Sore throat & Dry cough, fever & headache, shortness of breath & sore throat) (p > 0.05). Nonetheless, there was a statistically significant correlation amongst symptoms of cases of Coronavirus (sore throat & wet cough, fever & diarrhea, shortness of breath & wet cough) (p < 0.05). Conclusion: There was a negligible influence of the age of the patient on the sharpness of symptoms. Besides, the symptoms of Coronavirus in males were not remarkably different from those in females. Nevertheless, there was a notable association between fever and diarrhea, wet cough and shortness of breath, and wet cough and sore throat.

Downloads

Download data is not yet available.

References

Rodriguez-Morales AJ, Bonilla-Aldana DK, Balbin-Ramon GJ, Rabaan AA, Sah R, Paniz-Mondolfi A, et al. History is repeating itself: probable zoonotic spillover as the cause of the 2019 novel coronavirus epidemic. Infez Med. 2020; 28:3–5.

Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. China Novel Coronavirus Investigating and Research Team, A novel coronavirus from patients with pneumonia in China, 2019, N. Engl. J. Med. 2020;382 (8):727–733.

World Health Organization. https://www.who.int/dg/speeches/detail/whodirector- general-s-opening-remarks-at-the-mission-briefing-on-covid-19—12-march-2020. (accessed May 16, 2020).

Dong E, Du H, Gardner L. An interactive web-based dashboard to track COVID-19 in real-time. Lancet Infect Dis:2020;20:533–534.

Zhou P, Yang X-L, Wang X-G, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin, Nature. 2020;579(7798):270–273.

Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, et al. Epidemiology of COVID-19 among children in China. Pediatrics. 2020;145(6):e20200702

Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical characteristics of 138 hospitalized patients with 2019 Novel Coronavirusinfected pneumonia in Wuhan, China. JAMA. 2020;323:1061–1069.

Backer JA, Klinkenberg D, Wallinga J. Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travelers from Wuhan, China, 20–28 January 2020. Eurosurveillance. 2020;25:2000062.

Lauer SA, Grantz KH, Bi Q, Jones FK, Zheng Q, Meredith HR, et al. The incubation period of coronavirus disease 2019 (COVID-19) from publicly reported confirmed cases: estimation and application. Ann Int Med. 2020;172:577–582.

Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727–33.

Ortiz-Prado E, Simbaña-Rivera K, Gómez- Barreno L, Rubio-Neira M, Guaman LP, Kyriakidis NC, et al. Clinical, molecular, and epidemiological characterization of the SARS-CoV-2 virus and the Coronavirus Disease 2019 (COVID-19), a comprehensive literature review. Elsevier. 2020; 98:115094.

Fehr AR, Perlman S. Coronaviruses: An overview of their replication and pathogenesis. In: Coronaviruses: Methods and Protocols (New York: Springer). 2015;1282:1-23.

Chen Y, Liu Q, Guo D. Emerging coronaviruses: Genome structure, replication, and pathogenesis. J Med Virol. 2020;92:418–23.

Hoffmann M, Kleine-Weber H, Schroeder S, Mü MA, Drosten C, Pö S. SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell. 2020;181:271–80.

Cheng VCC, Chan JFW, To KKW, Yuen KY. Clinical management and infection control of SARS: Lessons learned. Antiviral Res. 2013;100:407–19.

Sun X, Wang T, Cai D, Hu Z, Chen J, Liao H, et al. Cytokine storm intervention in the early stages of COVID-19 pneumonia. Cytokine Growth Factor Rev. 2020;53:38–42.

Jin, J. M. et al. Gender Differences in Patients With COVID-19: Focus on Severity and Mortality. Frontiers in Public Health 8, (2020).

Lan F-Y, Filler R, Mathew S, Buley J, Iliaki E, Bruno-Murtha LA, et al. COVID-19 symptoms predictive of healthcare workers’ SARS-CoV-2 PCR results. PLoS ONE. 2020;15(6): e0235460.

Haitao T, Vermunt JV, Abeykoon J, Ghamrawi R, Gunaratne M, Jayachandran M, et al. COVID-19 and Sex Differences: Mechanisms and Biomarkers. Mayo Clin Proc. 2020;95(10):2189-2203.

Medina KL, Strasser A, Kincade PW. Estrogen influences the differentiation, proliferation, and survival of early B-lineage precursors. Blood. 2000;95(6):2059-2067.

Mohamed MO, Gale CP, Kontopantelis E, Kontopantelis E, Doran T, de Belder M, et al. Sex Differences in Mortality Rates and Underlying Conditions for COVID-19 Deaths in England and Wales. Mayo Clin Proc. 2020;95(10):2110-2124.

Sultan S, Altayar O, Siddique SM, Davitkov P, Feuerstein JD, Lim JK, et al. AGA Institute Rapid Review of the Gastrointestinal and Liver Manifestations of COVID-19, Meta-Analysis of International Data, and Recommendations for the Consultative Management of Patients with COVID-19. Gastroenterology. 2020;159(1):320-334.

Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497-506.

Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA. 2020;323(11):1061-1069.

Conti P, Ronconi G, Caraffa A, Gallenga CE, Ross R, Frydas I, et al. Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies. J Biol Regul Homeost Agents. 2020;34:1.

Johnson KD, Harris C, Cain JK, Hummer C, Goyal H, Perisetti A. Pulmonary and Extra-Pulmonary Clinical Manifestations of COVID-19. Front Med (Lausanne). 2020;7:526.

Downloads

Published

2023-04-14

How to Cite

Mustafa Karim Abdul-Husseein, Hajir Karim Abdul-Husseein, Karam Akram Al-Akkam, & Hala Saad Bash. (2023). Assessing the possible impact of patient’s demographic data on coronavirus symptoms. AVFT – Archivos Venezolanos De Farmacología Y Terapéutica, 40(8). Retrieved from http://caelum.ucv.ve/ojs/index.php/rev_aavft/article/view/26117