Microorganismos multirresistentes en la unidad de cuidados intensivos del Hospital General del Norte Los Ceibos, Ecuador

Authors

  • James Neira Borja
  • Cristóbal Espinoza Diaz
  • Clara Mejía Chele
  • José Mesías Ortega
  • Gloria Llerena Morales
  • Luis Toapanta Basantes
  • Alfredo Cassis Dahik
  • Duban Castañeda Morales
  • Gabriel Mendieta Marcillo
  • Lizeth Mosquera Meza
  • Karen Barragán Arias
  • Hugo Saquipay Ortega

Abstract

Objective: To evaluate the bacterial resistance patterns in the intensive care unit of the Hospital General del Norte Los Ceibos, Ecuador. Materials and methods: An observational, retrospective, and descriptive study was carried out in adult patients admitted to the intensive care unit of the aforementioned hospital, during the period January to July 2018, using the clinical data of the medical records department. Results: Of the 80 patients evaluated, the overall age was 55.6±12, 55% (n=44) were female, the most frequent pathologies were mechanical ventilation associated pneumonia (43.8%; n=35) followed by intravascular catheter associated infection (25%; n=20). The most common microorganisms were: Klebsiella pneumoniae (50%; n=40), Acinetobacter baumanii (25%; n=20), Staphylococcus epidermidis (18.8%; n=15), and Pseudomona aeuriginosa (6.25%; n=5). Colimycin and amikacin were the antibiotics with the highest sensitivity with 60 and 40%, respectively. Conclusion: There is a high percentage of bacterial resistance, especially to the main isolated microorganisms (Klebsiella pneumoniae and Acinetobacter baumanii), in samples taken from patients in the intensive care unit of the Hospital General del Norte Los Ceibos, Ecuador, with colistin and amikacin being the only therapeutic alternatives in this group of patients.

Keywords: epidemiology, infection, bacterial resistance, critical care, klebsiella spp.

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References

Lim C, Takahashi E, Hongsuwan M, et al. Epidemiology and burden of multidrug-resistant bacterial infection in a developing country. eLife. 2016; 5: e18082.

Arcos A. Análisis de pacientes portadores colonizados con bacterias multirresistentes en UCI en un hospital del norte de Quito en 2017. Titulo para optar al grado de Bioquímica Clínica. Universidad Central de Ecuador, 2019.

Amaya N. Resistencia Bacteriana en Unidad de Cuidados Intensivos Adultos de la Clínica Medilaser, Neiva-Colombia, entre Enero y Diciembre de 2008. Revista Facultad de Salud. 2009;1(2):31-37.

Morales A, Sánchez F, Agreda I, et al. Patrones de resistencia bacteriana en la unidad de cuidados intensivos del Hospital General Ambato del IESS, Ecuador. Archivos Venezolanos de Farmacología y Terapéutica. 2021;40(1):109-113.

Siwakoti S, Subedi A, Sharma A, et al. Incidence and outcomes of multidrug-resistant gram-negative bacteria infections in intensive care unit from Nepal- a prospective cohort study. Antimicrob Resist Infect Control. 2018;7:114.

Alkofide H, Alhammad AM, Alruwaili A, et al. Multidrug-Resistant and Extensively Drug-Resistant Enterobacteriaceae: Prevalence, Treatments, and Outcomes - A Retrospective Cohort Study. Infect Drug Resist. 2020;13:4653-4662.

Bhatia A, et al. Antibiotic resistance pattern in intensive care unit of a tertiary care teaching hospital. Int J Basic Clin Pharmacol 2018;7:906-11.

Paramythiotou E, Routsi C. Association between infections caused by multidrug-resistant gram-negative bacteria and mortality in critically ill patients. World J Crit Care Med. 2016; 5(2): 111–120.

Published

2023-03-30

How to Cite

Neira Borja, J. ., Espinoza Diaz, C. ., Mejía Chele, C. ., Mesías Ortega, J. ., Llerena Morales, G. ., Toapanta Basantes, L. ., Cassis Dahik, A. ., Castañeda Morales, D. ., Mendieta Marcillo, G. ., Mosquera Meza, L. ., Barragán Arias, K. ., & Saquipay Ortega, H. (2023). Microorganismos multirresistentes en la unidad de cuidados intensivos del Hospital General del Norte Los Ceibos, Ecuador. AVFT – Archivos Venezolanos De Farmacología Y Terapéutica, 40(5). Retrieved from http://caelum.ucv.ve/ojs/index.php/rev_aavft/article/view/25860