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Título : Endemic infection with HTLV-IIB in Venezuelan Indians: molecular characterization.
Autor : Leon-Ponte, Matilde
Echeverria de Perez, Gloria
Bianco Colmenares, Nicolás E.
Hengst, James
Dube, Syamalima
Lave, Jayne
Palabras clave : HTLV-IIB
Endemic infection
Venezuelan Indians
peripheral blood
Molecular Characterization
HTLV-II NRA
Fecha de publicación : 1998
Editorial : Journal of acquired immune deficiency syndromes and human retrovirology
Citación : Vol. 17;No. 5 pp 458-464
Resumen : The peripheral blood of 41 Yaruro and Guahibo Indians from Venezuela was examined for HTLV antibodies and DNA. Twenty-five samples (61%) were found to be infected with HTLV-IIB. The sensitivities of the serologic and DNA polymerase chain reaction (PCR) analyses were 80% and 96%, respectively. Epidemiologic studies supported both sexual and perinatal transmission of the virus. Sequence analyses of the HTLV-IIB strains from these Indians indicate that they are unique relative to HTLV-II detected in other groups of humans. HTLV-IIB-G2 isolated from a Guahibo Indian is the most divergent HTLV-IIB strain relative to the prototype HTLV-II NRA.
URI : http://hdl.handle.net/10872/14843
ISSN : 1077-9450
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