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http://hdl.handle.net/10872/14220
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| Título : | Seronegative spondyloarthropathies and HLA antigens in a Mestizo population |
| Autor : | Pérez R., Gloria E.
Paul M., Hernándo
Bianco Colmenares, Nicolás E.
Abadí, Isaac |
| Palabras clave : | HLA-A
antigens
Seronegative Spondyloarthropathies
Mestizo population
ankylosing spondylitis
spondylitic lesion |
| Fecha de publicación : | 1984 |
| Editorial : | Tissue Antigens |
| Citación : | Vol. 23;No. 2 pp 111-112 |
| Resumen : | HLA-A and -B antigens incidence were investigated in 100 cases of Seronegative Spondyloarthropathies and in 303 control individuals of a Venezuelan Mestizo population. Significative increased incidence of B27 was found among 69% of patients with ankylosing spondylitis and 68% with Reiter syndrome being the incidence in the control group of 2.9%. The B27 negative patients showed 40.4% positivity for Bw35, with spondylitic lesion in 12 ou t of 17 cases. Our results question the applicability of B27 as diagnostic criteria in the Mestizo patients bearers of a Seronegative Spondyloarthropathy and suggest the need to investigate further the role of antigens of the B locus in the pathophysiology of these clinical entities. |
| URI : | http://hdl.handle.net/10872/14220 |
| ISSN : | 1399-0039 |
| Aparece en las colecciones: | Artículos Publicados
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