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| Título : | Aporphine Alkaloids from Guatteria stenopelata (Annonaceae) |
| Autor : | Rodríguez, María del C.
Bastidas, Elsy
Rodríguez, Mildred
Lucena, Edgard
Castillo, Anibal
Hasegawa, Masahisa |
| Palabras clave : | Guatteria stenopelata
dicentrinone
N-methyldicentrinone
4,5-dioxodehydrodixentrine
MAO-B
Annonaceae
porphine alkaloids |
| Fecha de publicación : | 2008 |
| Editorial : | Natural Products Communications |
| Citación : | Volumen 3, Number 4, Pages 515-518 (2008) |
| Resumen : | Guatteria species (Annonaceae) are rich in isoquinoline alkaloids that contain a restricted beta phenethylamine moiety and thus have potential monoamine oxidase (MAO) inhibitor for treatment of Alzheimer´s and Parkinson´s diseases. Three aporphine alkaloids have bee isolate from G. stenopelata, the know oxoaporphine dicentrinone (1), and two novel compounds, N-methyldicentrinone (2) and 4,5-dioxodehydrodixentrine (3). Their inhibitory effects on MAO-B were evaluated, but none of them was significantly active. |
| URI : | http://hdl.handle.net/10872/14052 |
| ISSN : | 1555-9475 |
| Aparece en las colecciones: | Artículos Publicados
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