SABER UCV >
1) Investigación >
Artículos Publicados >
Por favor, use este identificador para citar o enlazar este ítem:
http://hdl.handle.net/10872/12074
|
| Título : | IMMUNOPATHOLOGY OF HUMAN SCHISTOSOMIASIS MANSONI. II. NK ACTIVITY AND STIMULATION BY SPECIFIC ANTIGEN |
| Autor : | BENARROCH, O.
Noya, Oscar
Alarcon de Noya, Belkisyole
BLANCA, I.
Bianco Colmenares, Nicolás E. |
| Palabras clave : | Natural Killer cells
S. mansoni |
| Fecha de publicación : | 1988 |
| Editorial : | Rev. Inst. Med. trop. Sao Paulo |
| Citación : | vOL. 30;6 |
| Resumen : | Sixteen S. mansoni infected and untreated patients (5 with recent infection
and 11 with chronic disease) were evaluated for their in v i t r o natural killer ( N K )
activity against the N K sensitive target K562 cell line. N K levels in 9 out of 11
patients (82%) w i th chronic disease were significantly lower (mean = 15 ± 6%),
compared with patients recently infected (mean = 41 ± 9% p < 0.001) and with
the control group (mean = 38 ± 13% p < 0.001). However, both patients and controls
N K activity was stimulated by soluble adult worm antigens (SAWA) , indicating
that N K function even in the chronic stage of the infection is able to respond to
the parasite antigens. Thes e results suggest the possibility of N K cell participati on
as effector mechanism against S . mansoni. |
| URI : | http://hdl.handle.net/10872/12074 |
| Aparece en las colecciones: | Artículos Publicados
|
Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.
|
