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Buscar por Autor Benaim, G
Mostrando resultados 1 a 20 de 21
| Fecha de publicación | Título | Autor(es) | | 2015 | The Activating Role of Phospho-(Tyr)-Calmodulin on the Epidermal Growth Factor Receptor. Biochem. J. 472: 195-204 | Stateva, S.R; Salas, V; Benguría, A; Cossío, I; Anguita, E; Martín-Nieto, J; Benaim, G; Villalobo, A |
| 2023 | Breaking Ground in Chagas Disease Treatment: Unveiling Novel Drug Targets and Drug Repurposing Strategies". Frontiers in Cellular and Infection Microbiology Specialty Section: Clinical Microbiology 13:1199715. doi: 10.3389/fcimb.2023.1199715. eCollection 2023. | Dushak, V; Paniz-Mondolfi, A; Benaim, G |
| 2015 | Ca2+/Camodulin and Apo-Calmodulin Both Bind to and Enhance the Tyrosine Kinase Activity of c-Src. PLoS One June, 9 ;10 (6):e0128783. doi: 10.1371/journal.pone.0128783. eCollection 2015. PMID: 26058065 | Stateva, S.R; Salas, V; Anguita, E; Benaim, G; Villalobo, A |
| 2015 | Characterization of phospho-(tyrosine)-mimetic calmodulin mutants. PLoS One Apr 1;10(4):e0120798. doi: 10.1371/journal.pone.0120798. eCollection 2015 | Stateva, S.R; Salas, V; Benaim, G; Menéndez, M; Solís, D; Villalobo, A |
| 2020 | Determination of intracellular Ca2+ concentration on the human pathogens trypanosomatids Leishmania mexicana and Trypanosoma cruzi by the use of the fluorescent Ca2+ indicator Fura-2. Bioprotocols. 10(18): e3766. DOI:10.21769/BioProtoc.3766 | Rey-Cibati, A; Valladares-Delgado, M; Benaim, G |
| 2020 | Disruption of intracellular calcium homeostasis as a therapeutic target against Trypanosoma cruzi. Frontiers Cell. Infect. Microbiol.10: 46. doi: 10.3389/fcimb.2020.00046 | Benaim, G; Paniz-Mondolfi, A; Sordillo, M; Martinez-Sotillo, N |
| 2016 | Drug repositioning for neglected tropical protozoan diseases. Curr. Top. Med. Chem. 16: 2201-2222 | Sbaraglini, M; Vanrell, M.C; Bellera, C.L; Benaim, G; Carrillo, C; Talevi, A; Romano, P |
| 2021 | Editorial: Advances in the Molecular Biology of Trypanosomatid Pathogens: New Strategies Against Ancient Enemies. Front. Cell. Infect. Microbiol. 11:777008.doi: 10.3389/fcimb.2021.777008 | Benaim, G; Paniz-Mondolfi, A; Ramírez, J; Sordillo, E |
| 2017 | Efecto de un metilen-dioxiflavonoide aislado de Iresine diffusa sobre la viabilidad celular de Leishmania mexicana y la homeostasis intracelular del Ca2+. Invest. Clín. 58: 334-351. | De Gouveia, Y; Hernández-Rodríguez, V; Rodríguez-Durán, J; Suárez, A; Benaim, G |
| 2022 | Effect of Tetrahydroquinoline Derivatives on the Intracellular Ca2+ Homeostasis in Breast Cancer Cells (MCF-7) and its Relationship with Apoptosis. Invest. Clin. 63: 243-261 | Maksoud, S; Mayora, A; Colman, L; Sojo, F; Pimentel, A; Kouznetsov, V; Merchán-Arenas, D; Romero, A; Arvelo, F; De Sanctis, J; Benaim, G |
| 2012 | El Ca2+ y los esfingolípidos como moduladores de la apoptosis y el cáncer. Invest. Clin 53: 84-110 | Pimentel, A; Benaim, G |
| 2019 | Identification and Electrophysiological Properties of a Sphingosine-dependent Plasma Membrane Ca2+ Channel in Trypanosoma cruzi. FEBS J. 286: 3909-3925. doi: 10.1111/febs.14947 | Rodriguez-Duran, J; Pinto-Martinez, A; Castillo, C; Benaim, G |
| 2016 | Inhibition of Leishmania mexicana Growth by the Tuberculosis Drug SQ109. Antimicrob Agents Chemother. 60: 6386-6389 | García-García, V; Oldfield, E; Benaim, G |
| 2012 | In vitro anti-Trypanosoma cruzi activity of dronedarone, a novel amiodarone derivative with an improved safety profile. Antimicrob. Agents Chemother. 56: 3720-3725 | Benaim, G; Hernandez-Rodriguez, V; Mujica, S; Plaza-Rojas, L; Silva, M.L; Parra, N; Garcia-Marchan, Y; Paniz-Mondolfi, A; Uzcanga, G |
| 2018 | Mechanism of Action of Miltefosine on Leishmania donovani Involves the Impairment of Acidocalcisome Function and the Activation of the Sphingosine-Dependent Plasma Membrane Ca2+ Channel. Antimicrob Agents Chemother. 62: 1-10 | Pinto-Martinez, A; Rodriguez-Durán, J; Serrano-Martin, X; Hernandez-Rodriguez, V; Benaim, G |
| 2024 | Molecular, immunological and physiological evidences of a sphingosine-activated plasma membrane Ca2+-channel in Trypanosoma equiperdum. Parasitol. Res. 2024. 123: 166-182 | Pérez-Gordones, M.C.; Ramírez-Iglesias, J.R.; Benaim, G; Meandoza, M. |
| 2015 | SQ109: A New Drug Lead for Chagas Disease. Antimicrob Agents Chemother. 59: 50-61 | Veiga-Santos, P; Li, K; Lameira, L; de Carvalho, T.M; Huang, G; Galizzi, M; Shang, N; Li, Q; Gonzalez-Pacanowska, G; Hernandez-Rodriguez, V; Benaim, G; Guo, R.T; Urbina, J.A; Docampo, R; de Souza, W; Oldfield, E |
| 2023 | Synthesis, Antimalarial, Antileishmanial, and Cytotoxicity Activities and Preliminary In Silico ADMET Studies of 2-(7-Chloroquinolin-4-ylamino) ethyl Benzoate Derivatives. Pharmaceuticals 2023, 16, 1709. https://doi.org/ 10.3390/ph16121709 | Gutiérrez, E J; Ramírez, H; Fernandez-Moreira, E; Acosta, M.E; Mijares, J.B M.R..De Sanctis; Gurská, S; Džubák, P; Hajdúch, M; Labrador-Fagúndez, L; Stella, B. G; Diaz-Perez, L.J; Benaim, G; Charris, J.E |
| 2016 | Synthesis of Ergosterone-coupled Triazol and characterization of their biological activity on Leishmania mexicana promastigotes: Induction of mitochondrial dysfunction, oxidative stress, and acidocalcisomes Ca2+ release. Microbial Cell. 3: 14-28 | Figarella, K; Marsiccobetre, S; Arocha, I; Colina, W; Hasegawa, M; Rodriguez, M; Duszenko, M; Benaim, G; Uzcategui, N |
| 2024 | Unmasking the mechanism behind Miltefosine: Revealing the disruption of intracellular Ca2+ homeostasis as a rational therapeutic target in leishmaniasis and Chagas disease. Biomolecules 2024, 14, 406. https://doi.org/10.3390/biom14040406 | Benaim, G; Paniz-Mondolfi, A |
Mostrando resultados 1 a 20 de 21
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